Author

M. Gutierrez-Arcelus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 5

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Research Focus:cell type annotation· 5 Research Focus:differential expression· 5 Organism:human· 5 Assay:bulk RNA-seq· 4 Approach:experimental assay· 4 Assay:scRNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Assay:flow cytometry· 2

Frequent Co-Authors

S. Raychaudhuri· 3 shared J. A. Boyce· 2 shared J. Keegan· 2 shared K. Slowikowski· 2 shared M. Lee· 2 shared N. Bhattacharyya· 2 shared T. M. Eisenhaure· 2 shared T. M. Laidlaw· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

S. Raychaudhuri

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5 papers

Recent·Most cited

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

A. Horisberger, A. Griffith, J. Keegan, A. Arazi, J. Pulford, E. Murzin, K. Howard, B. Hancock, A. Fava, T. Sasaki, T. Ghosh, J. Inamo, R. Beuschel, Y. Cao, K. Preisinger, , Accelerating Medicines Pa

The paper identifies three immunologically distinct groups in lupus nephritis patients based on blood immunophenotyping, correlating with histopathology, treatment response, and renal outcomes.

bioRxiv · Jan 14, 2024Immunology

Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps

N. A. Barrett, G. X. Huang, N. R. Hallen, M. Lee, K. Zheng, X. Wang, M. V. Mandanas, S. Djeddi, D. Fernandez, J. Hacker, T. Ryan, R. W. Bergmark, N. Bhattacharyya, S. Lee, A. Z. Maxfield, , M. Gutierrez-Arcelus

The paper identifies increased mTORC1 activity in CRSwNP epithelial cells and links it to cytokine production and inflammation in both CRSwNP and asthma.

bioRxiv · Oct 13, 2023 · PreprintImmunology

Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling

X. Wang, N. Hallen, M. Lee, S. Samuchiwal, Q. Ye, K. Buchheit, A. Maxfield, R. Roditi, R. Bergmark, N. Bhattacharyya, T. Ryan, D. Gakpo, S. Raychaudhuri, D. Dwyer, T. M. Laidlaw, , N. Barrett

This study identifies BCAM as a marker of airway basal stem cells and shows that T2 cytokines drive their expansion via IRS signaling in CRSwNP.

bioRxiv · Oct 13, 2022Immunology

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

L. T. Donlin, D. A. Rao, K. Wei, K. Slowikowski, M. J. McGeachy, J. D. Turner, N. Meednu, F. Mizoguchi, M. Gutierrez-Arcelus, D. J. Lieb, J. Keegan, K. Muskat, J. Hillman, C. Rozo, E. Ricker, , M. B Brenner

This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.

bioRxiv · Mar 19, 2018Immunology

A genome-wide innateness gradient defines the functional state of human innate T cells

M. Gutierrez-Arcelus, N. Teslovich, A. R. Mola, H. Kim, S. Hannes, K. Slowikowski, G. F. M. Watts, M. Brenner, S. Raychaudhuri, P. J. Brennan

The paper identifies an innateness gradient in human T cells, showing a trade-off between effector function and proliferative capacity.

bioRxiv · Mar 13, 2018Immunology