Author

P. J. Jardine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 4 Organism:bacteria (other)· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. A. Antson· 1 shared A. Huet· 1 shared A. Tong· 1 shared B. P. Mahler· 1 shared C. Bustamante· 1 shared C. G. Baumann· 1 shared C. V. Robinson· 1 shared D. E. Smith· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperBiochemistry

A. A. Antson

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5 papers

Recent·Most cited

Role of DNA-DNA sliding friction and non-equilibrium dynamics in viral genome ejection and packaging

M. Fizari, N. Keller, P. J. Jardine, D. E. Smith

This study investigates DNA ejection dynamics from viral capsids, finding that DNA-DNA sliding friction and clogging control ejection but not packaging.

bioRxiv · Apr 3, 2023 · PreprintBiophysics

Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system

H. K. H. Fung, S. Grimes, A. Huet, R. L. Duda, M. Chechik, J. Gault, C. V. Robinson, R. W. Hendrix, P. J. Jardine, J. F. Conway, C. G. Baumann, A. A. Antson

This study describes the structural and biochemical mechanisms of DNA packaging by the HK97 bacteriophage's terminase complex, revealing similarities to other viral systems.

bioRxiv · May 10, 2022Biochemistry

The NMR structure of a vestigial nuclease provides insight into the evolution of functional transitions in viral dsDNA packaging motors

B. P. Mahler, P. J. Bujalowski, H. Mao, E. A. Dill, P. J. Jardine, K. H. Choi, M. Morais

The paper reports the NMR structure of a vestigial nuclease domain in phi29 ATPase, revealing its evolutionary origin and role in DNA packaging motor function.

Nucleic Acids Research · Nov 18, 2020Peer-reviewedBiophysics

A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA

M. Woodson, J. Pajak, W. Zhao, W. Zhang, G. Arya, M. A. White, P. J. Jardine, M. C. Morais

The paper shows that viral DNA packaging motors switch between helical and planar symmetry to translocate double-stranded DNA.

bioRxiv · May 23, 2020Biophysics

A DNA translocase operates by cycling between planarand lock-washer structures

J. P. Castillo, A. Tong, S. Tafoya, P. J. Jardine, C. Bustamante

The paper studies a DNA translocase that adapts its translocation mechanism to different substrates by altering its structural conformation.

bioRxiv · May 22, 2020 · PreprintBiophysics