Author

P. J. Sikorski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. Jemielity· 3 shared J. Kowalska· 3 shared M. Warminski· 3 shared D. Nowis· 2 shared A. Depaix· 1 shared A. Mamot· 1 shared A. Popielec· 1 shared B. A. Shimanski· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

J. Jemielity

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Author profile →

3 papers

Recent·Most cited

Trinucleotide mRNA cap analog N6-benzylated at the site of posttranscriptional m6Am mark facilitates mRNA purification and confers superior translational properties in vitro and in vivo

M. Warminski, E. Trepkowska, M. Smietanski, P. J. Sikorski, M. R. Baranowski, M. Bednarczyk, H. Kedzierska, B. Majewski, A. Mamot, D. Papiernik, A. Popielec, R. Serwa, B. A. Shimanski, P. Sklepkiewicz, M. Sklucka, , J. Kowalska

This paper introduces a modified mRNA cap analog, AvantCap, which improves mRNA purification and translational efficiency in vitro and in vivo.

bioRxiv · Nov 10, 2023 · PreprintBiochemistry

2'-O -methylation of the second transcribed nucleotide within mRNA 5' cap impacts protein production level in a cell specific manner and contributes to RNA immune evasion

K. Drazkowska, N. Baran, M. Warminski, R. Tomecki, A. Depaix, D. Cysewski, R. Kasprzyk, J. Kowalska, J. Jemielity, P. J. Sikorski

This study shows that 2'-O-methylation of the second transcribed nucleotide in mRNA 5' cap affects protein production levels and contributes to RNA immune evasion in a cell-specific manner.

bioRxiv · Feb 3, 2022Biochemistry

The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells

P. J. Sikorski, M. Warminski, D. Kubacka, T. Ratajczak, D. Nowis, J. Kowalska, J. Jemielity

bioRxiv · Nov 25, 2019Biochemistry