Author

P. J. Wittkopp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 5 Animal Behavior & Cognition· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 4 Organism:yeast· 4 Assay:DNA methylation· 3 Organism:Drosophila· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Hodgins-Davis· 2 shared B. P. H. Metzger· 2 shared E. A. Walker· 2 shared F. Duveau· 2 shared A. M. Lamb· 1 shared B. Yang· 1 shared D. Chung· 1 shared D. L. Stern· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersEvolutionary Biology

A. Hodgins-Davis

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Active compensation for changes in TDH3 expression mediated by direct regulators of TDH3 in Saccharomyces cerevisiae

P. Vande Zande, P. J. Wittkopp

The paper investigates active compensation for reduced TDH3 expression in yeast by its paralogs TDH1 and TDH2, showing upregulation mediated by Gcr1p and Rap1p.

bioRxiv · Jan 13, 2023Cell Biology

ebony affects pigmentation divergence and cuticular hydrocarbons in Drosophila americana and D. novamexicana

A. M. Lamb, Z. Wang, P. Simmer, H. Chung, P. J. Wittkopp

This study tests the role of the ebony gene in pigmentation and cuticular hydrocarbon divergence between Drosophila americana and D. novamexicana using CRISPR/Cas9 mutants.

bioRxiv · Mar 5, 2020Evolutionary Biology

The yellow gene influences Drosophila male mating success through sex comb melanization

J. H. Massey, D. Chung, I. Siwanowicz, D. L. Stern, P. J. Wittkopp

This study identifies that the yellow gene affects Drosophila male mating success by altering sex comb melanization, not through neural or behavioral changes.

bioRxiv · Jun 18, 2019Animal Behavior & Cognition

Complex polymorphic genetic architecture underlies trans-regulatory variation among strains of Saccharomyces cerevisiae

B. P. H. Metzger, P. J. Wittkopp

The paper identifies trans-regulatory variation affecting TDH3 promoter activity in Saccharomyces cerevisiae strains, showing stabilizing selection maintains alleles with opposing effects.

bioRxiv · Mar 4, 2019 · PreprintEvolutionary Biology

Empirical measures of mutational effects define neutral models of regulatory evolution in Saccharomyces cerevisiae

A. Hodgins-Davis, F. Duveau, E. A. Walker, P. J. Wittkopp

The paper measures mutational effects on gene expression in yeast to show that neutral processes may explain more expression variation than previously thought.

bioRxiv · Feb 17, 2019Evolutionary Biology

Redundant and cryptic enhancer activities of the Drosophila yellow gene

G. Kalay, J. Lachowiec, U. Rosas, M. R. Dome, P. J. Wittkopp

The paper examines the evolution of cis-regulatory sequences of the Drosophila yellow gene, finding redundant and cryptic enhancer activities across species.

bioRxiv · Sep 27, 2018Evolutionary Biology

Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

F. Duveau, A. Hodgins-Davis, B. P. H. Metzger, B. Yang, S. Tryban, E. A. Walker, P. Lybrook, P. J. Wittkopp

The paper quantifies how altering gene expression noise in yeast affects fitness, showing it can be beneficial or deleterious depending on average expression levels.

bioRxiv · Apr 3, 2018Evolutionary Biology