Author

P. K. Javaregowda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. UMEZAWA· 3 shared A. Nakazawa· 2 shared H. Nonaka· 2 shared K. Ite· 2 shared M. Kasahara· 2 shared M. Toyoda· 2 shared N. Saku· 2 shared S. Miyata· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

A. UMEZAWA

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Author profile →

3 papers

Recent·Most cited

Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3

C. Kobori, R. Takagi, R. Yokomizo, S. Yoshihara, M. Mori, H. Takahashi, P. K. Javaregowda, T. Akiyama, M. S. H. Ko, K. Kishi, A. UMEZAWA

This study generates functional and long-lived melanocytes from human pluripotent stem cells using transient JMJD3 expression, showing melanogenesis and engraftability in mice.

bioRxiv · Mar 3, 2023Cell Biology

Puromycin selection of cells with a high expression of the cytochrome P450 CYP3A4 gene activity from a patient with drug-induced liver injury (DILI) and their lifespan prolongation using a combination of CDK4R24C, cyclin D1 and TERT

S. Miyata, N. Saku, P. K. Javaregowda, K. Ite, M. Toyoda, T. Kimura, H. Nishina, A. Nakazawa, M. Kasahara, H. Nonaka, T. Kiyono, A. Umezawa

The paper generates an immortalized hepatocyte cell line with high CYP3A4 expression from a DILI patient and shows its prolonged lifespan and drug-metabolism capacity.

bioRxiv · Apr 25, 2020 · PreprintCell Biology

Ammonia-based enrichment and long-term propagation of zone I hepatocyte-like cells

R. Tsuneishi, N. Saku, S. Miyata, P. K. Javaregowda, K. Ite, M. Toyoda, T. Kimura, M. Kuroda, A. Nakazawa, M. Kasahara, H. Nonaka, A. Kamiya, T. Kiyono, J. Yamauchi, A. Umezawa

This study shows that ammonia treatment enriches hepatocyte-like cells derived from human pluripotent stem cells, which can be propagated long-term in vitro while maintaining liver-specific gene expression.

bioRxiv · Mar 20, 2020Cell Biology