Author

P. Kaye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Ashwin· 2 shared K. Van Bocxlaer· 2 shared A. L. Goundry· 1 shared A. Layton· 1 shared A. P. C. A. Lima· 1 shared B. T. Dias· 1 shared B. Vojtkova· 1 shared C. Jaffe· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

H. Ashwin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

UVB modifies skin immune-stroma cross-talk and promotes effector T cell recruitment during cryptic Leishmania donovani infection

M. Montes de Oca, S. Dey, K. Van Bocxlaer, H. Ashwin, N. Brown, E. Myburgh, N. S. Dey, G. F. Rani, E. Muscutt, M. Osman, D. Perez-Mazliah, S. James, L. Gilbert, M. Chatterjee, P. Kaye

This study uses scRNA-seq and spatial transcriptomics to show UVB exposure alters immune-stromal interactions and T cell recruitment during cryptic Leishmania donovani infection.

bioRxiv · Feb 3, 2023 · PreprintImmunology

Tissue specific dual RNA-seq defines host-parasite interplay in murine visceral leishmaniasis caused by Leishmania donovani and Leishmania infantum

S. Forrester, A. L. Goundry, B. T. Dias, T. Leal-Calvo, M. Moraes, P. Kaye, J. Mottram, A. P. C. A. Lima

This study uses dual RNA-seq to compare host and parasite gene expression in mouse models of Leishmania donovani and Leishmania infantum infections, identifying common and species-specific transcriptional responses.

bioRxiv · Feb 4, 2022Microbiology

Characterization of a new Leishmania major isolate for use in a controlled human infection model

H. Ashwin, J. Sadlova, B. Vojtkova, T. Becvar, P. Lypaczewski, E. Schwartz, E. Greensted, K. Van Bocxlaer, M. Pasin, K. Lipinski, V. Parkash, G. Matlashewski, A. Layton, C. Lacey, C. Jaffe, , P. Kaye

This paper isolates and characterizes a new Leishmania major strain for use in controlled human infection models to advance vaccine development.

bioRxiv · Aug 12, 2020Microbiology