P. Lypaczewski

Prevalent chromosome fusion in Vibrio cholerae O1

The paper reports chromosome fusions in clinical V. cholerae O1 isolates, showing stable transmission between patients within a household.

Diversity of Vibrio cholerae O1 through the human gastrointestinal tract during cholera

This study compares genetic diversity of Vibrio cholerae O1 in vomit and stool from cholera patients, finding reduced diversity in stool and some gene loss between samples.

Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis

This study shows that centrin-deficient L. mexicana parasites protect against Old World visceral leishmaniasis in a hamster model by reducing parasite burden and altering cytokine responses.

Evidence that interspecies Leishmania hybrids contribute to changes in disease pathology

This study identifies interspecies Leishmania hybrids in Sri Lanka that may explain atypical cutaneous leishmaniasis, suggesting hybridization contributes to disease pathology changes.

Characterization of a new Leishmania major isolate for use in a controlled human infection model

This paper isolates and characterizes a new Leishmania major strain for use in controlled human infection models to advance vaccine development.

A Second Generation Leishmanization Vaccine with a Markerless Attenuated Leishmania major Strain using CRISPR gene editing

This paper describes a CRISPR-edited Leishmania major strain for a second-generation leishmanization vaccine that is marker-free and safe, showing protection in mice comparable to traditional leishmanization.