Author

P. L. Hsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

N. Zheng· 3 shared C. Chatterjee· 2 shared A. K. Michael· 1 shared A. Srivastava· 1 shared B. Roeder· 1 shared C. E. Weller· 1 shared C. J. A. Leonen· 1 shared C. L. Partch· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

N. Zheng

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Author profile →

3 papers

Recent·Most cited

Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts

C. J. A. Leonen, M. Shimada, C. E. Weller, T. Nakadai, P. L. Hsu, P. M. M. Shelton, M. Sadilek, N. Zheng, B. Roeder, C. Chatterjee

This study shows that sumoylation of H4K12 inhibits p300-mediated transcription and H3K4 methylation in vitro.

bioRxiv · Apr 8, 2021Biochemistry

Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms

J. L. Fribourgh, A. Srivastava, C. R. Sandate, A. K. Michael, P. L. Hsu, C. Rakers, L. T. Nguyen, M. R. Torgrimson, G. C. G. Parico, S. Tripathi, N. Zheng, G. C. Lander, T. Hirota, F. Tama, C. L. Partch

The paper identifies a dynamic loop in cryptochromes that regulates their differential binding to CLOCK:BMAL1, explaining their distinct roles in circadian rhythms.

bioRxiv · Aug 20, 2019 · PreprintBiochemistry

Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS

P. L. Hsu, H. Shi, C. Leonen, J. Kang, C. Chatterjee, N. Zheng

This study determines the cryo-EM structure of the COMPASS complex bound to H2Bub and nucleosome, revealing how H2Bub activates H3K4 methylation by modulating the Set1 ARM.

bioRxiv · Aug 20, 2019Biochemistry