Author

J. L. Fribourgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. L. Partch· 3 shared G. C. G. Parico· 3 shared A. B. Chan· 1 shared A. K. Michael· 1 shared A. Srivastava· 1 shared B. N. Hernandez· 1 shared C. R. Sandate· 1 shared C. Rakers· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiochemistry

C. L. Partch

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Author profile →

3 papers

Recent·Most cited

CRY2 missense mutations suppress P53 and enhance cell growth

A. B. Chan, G. C. G. Parico, J. L. Fribourgh, L. H. Ibrahim, M. J. Bollong, C. L. Partch, K. A. Lamia

The paper identifies CRY2 mutations that suppress P53 and enhance cell growth by disrupting interactions with SCFFBXL3 and affecting circadian rhythms.

bioRxiv · Jan 8, 2021Cell Biology

The CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1

G. C. G. Parico, I. Perez, J. L. Fribourgh, B. N. Hernandez, H.-W. Lee, C. L. Partch

The study identifies the CRY1 tail's role in regulating its interaction with CLOCK:BMAL1, affecting circadian timing and linking it to Delayed Sleep Phase Disorder.

bioRxiv · Sep 5, 2019Biochemistry

Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms

J. L. Fribourgh, A. Srivastava, C. R. Sandate, A. K. Michael, P. L. Hsu, C. Rakers, L. T. Nguyen, M. R. Torgrimson, G. C. G. Parico, S. Tripathi, N. Zheng, G. C. Lander, T. Hirota, F. Tama, C. L. Partch

The paper identifies a dynamic loop in cryptochromes that regulates their differential binding to CLOCK:BMAL1, explaining their distinct roles in circadian rhythms.

bioRxiv · Aug 20, 2019 · PreprintBiochemistry