Author

P. Legoix

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Hamza· 1 shared A. Luscan· 1 shared A. Michaud· 1 shared A. Moreau· 1 shared A. Vincent-Salomon· 1 shared A. Williart· 1 shared A. Yatim· 1 shared A.-M. Lennon-Dumenil· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Hamza

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition

P. Romero, L. Richart, S. Aflaki, M. Burton, A. Michaud, J. Masliah-Planchon, F. Kuhnoswki, C. Meaudre, A. Luscan, A. Hamza, P. Legoix, A. Vincent-Salomon, M. Wassef, D. Holoch, R. Margueron

This study shows that EZH2 mutations in follicular lymphoma alter H3K27 methylation and transcriptional responses to PRC2 inhibition, with clinical implications for patient stratification.

bioRxiv · Jan 2, 2023Cancer Biology

A Shape Sensing Mechanism driven by Arp2/3 and cPLA2 licenses Dendritic Cells for Migration to Lymph Nodes in Homeostasis

Z. Alraies, C. A. Rivera, M.-G. Delgado, D. Sanseau, M. Maurin, R. Amadio, G. Maria Piperno, G. Dunsmore, A. Yatim, L. Lacerda Mariano, P. Saez, M. Gratia, O. Lamiable, A. Moreau, A. Williart, , A.-M. Lennon-Dumenil

The paper identifies a shape sensing mechanism in dendritic cells that links cell motility to CCR7 expression, enabling migration to lymph nodes through ARP2/3-cPLA2 signaling.

bioRxiv · Aug 9, 2022Cell Biology