A Shape Sensing Mechanism driven by Arp2/3 and cPLA2 licenses Dendritic Cells for Migration to Lymph Nodes in Homeostasis
Z. Alraies, C. A. Rivera, M.-G. Delgado, D. Sanseau, M. Maurin, R. Amadio, G. Maria Piperno, G. Dunsmore, A. Yatim, L. Lacerda Mariano, P. Saez, M. Gratia, O. Lamiable, A. Moreau, A. Williart, , A.-M. Lennon-Dumenil
The paper identifies a shape sensing mechanism in dendritic cells that links cell motility to CCR7 expression, enabling migration to lymph nodes through ARP2/3-cPLA2 signaling.
bioRxiv · Aug 9, 2022Cell Biology