Author

A. Michaud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Organism:Xenopus· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. B. Goryachev· 3 shared J. Landino· 3 shared M. Leda· 3 shared S. Kim· 2 shared W. Bement· 2 shared W. M. Bement· 2 shared Z. T. Swider· 2 shared A. G. Vecchiarelli· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

A. B. Goryachev

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Energy partitioning in the cell cortex

S. Chen, D. Seara, A. Michaud, S. Kim, W. Bement, M. Murrell

The paper measures energy partitioning between chemical and mechanical subsystems in the cell cortex and finds that energy distribution changes with Rho GTPase pathway manipulation.

bioRxiv · May 6, 2024Biophysics

Synergistic activity of IL-2 mutein with tolerogenic ImmTOR nanoparticles leads to massive expansion of antigen-specific Tregs and protection against autoimmune disease

T. K. Kishimoto, M. Fournier, A. Michaud, G. Rizzo, C. Roy, T. Capela, N. Nukolova, N. Li, L. Doyle, F.-n. Fu, D. VanDyke, P. G. Traber, J. B. Spangler, S. S. Leung, P. O. Ilyinskii

This study shows that combining IL-2 mutein with ImmTOR nanoparticles expands antigen-specific Tregs and protects against autoimmune diseases.

bioRxiv · May 15, 2023 · PreprintImmunology

Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells

X. Yang, J. L. Smith, M. T. Beck, J. M. Wilkinson, A. Michaud, J. D. Vasta, M. B. Robers, T. M. Willson

The paper develops a NanoBRET probe to measure PLK1 target engagement in live cells and evaluates its use with known PLK inhibitors.

bioRxiv · Feb 25, 2023 · PreprintCell Biology

EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition

P. Romero, L. Richart, S. Aflaki, M. Burton, A. Michaud, J. Masliah-Planchon, F. Kuhnoswki, C. Meaudre, A. Luscan, A. Hamza, P. Legoix, A. Vincent-Salomon, M. Wassef, D. Holoch, R. Margueron

This study shows that EZH2 mutations in follicular lymphoma alter H3K27 methylation and transcriptional responses to PRC2 inhibition, with clinical implications for patient stratification.

bioRxiv · Jan 2, 2023Cancer Biology

A versatile pattern-forming cortical circuit based on Rho, F-actin, Ect2 and RGA-3/4

A. Michaud, M. Leda, Z. T. Swider, S. Kim, J. He, J. Landino, J. R. Valley, J. Huisken, A. B. Goryachev, G. von Dassow, W. Bement

The paper identifies Ect2 and RGA-3/4 as core components of a cortical excitability circuit and demonstrates the immature Xenopus oocyte as a model for studying excitable dynamics.

bioRxiv · Mar 8, 2022Cell Biology

Cell cycle and developmental control of cortical excitability in Xenopus laevis

Z. T. Swider, A. Michaud, M. Leda, J. Landino, A. B. Goryachev, W. M. Bement

This study quantifies the onset and changes in cortical excitability in Xenopus laevis eggs and embryos, linking wave properties to cell cycle progression and cell size.

bioRxiv · Feb 11, 2022 · PreprintCell Biology

Rho and F-actin self-organize within an artificial cell cortex

J. Landino, M. Leda, A. Michaud, Z. Swider, M. Prom, C. M. Field, W. M. Bement, A. G. Vecchiarelli, A. B. Goryachev, A. L. Miller

This study creates an artificial cell cortex using Xenopus egg extract and lipid bilayers to observe self-organizing Rho and F-actin dynamics similar to those in vivo.

bioRxiv · Apr 9, 2021Cell Biology