P. Mamidi

The uniqueness of the Brazilian Yellow Fever Virus. Are the vaccines less effective against it?

The study identifies two unique amino acid substitutions in Brazilian YFV strains that may reduce vaccine effectiveness by altering epitope binding.

DNA damage response signaling is crucial for effective Chikungunya virus replication

This study shows that Chikungunya virus (CHIKV) infection activates DNA damage response (DDR) pathways, increases DNA damage, and interacts with Chk2 and Chk1 to facilitate viral replication and cell cycle arrest.

Telmisartan restricts Chikungunya virus infection in vitro and in vivo through the AT1/ PPAR-γ/MAPKs pathways

This study shows Telmisartan reduces Chikungunya virus infection in vitro and in vivo by modulating host pathways including AT1/PPAR-γ/MAPKs.

MK2a inhibitor CMPD1 abrogates chikungunya virus infection by modulating actin remodeling pathway

This study shows that MK2 and MK3 inhibition with CMPD1 reduces CHIKV infection by blocking actin remodeling and viral release, with potential for antiviral development.

Molecular epidemiology of Japanese Encephalitis Virus in pig population of Odisha, Assam and Manipur states of India

This study investigates JEV prevalence and molecular epidemiology in pigs from three Indian states, finding higher infection rates in Manipur and identifying genotype III as dominant with specific mutations.