Author

T. K. Nayak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Datey· 3 shared S. Chattopadhyay· 3 shared S. De· 3 shared E. Laha· 2 shared P. Mamidi· 2 shared S. Chatterjee· 2 shared S. Kumar· 2 shared A. Kumar· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMicrobiology

A. Datey

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA damage response signaling is crucial for effective Chikungunya virus replication

S. Chatterjee, S. Kumar, P. Mamidi, A. Datey, S. Sengupta, C. Mahish, E. Laha, S. De, S. S. Keshry, T. K. Nayak, S. Ghosh, S. Singh, B. B. Subudhi, S. Chattopadhyay, S. Chattopadhyay

This study shows that Chikungunya virus (CHIKV) infection activates DNA damage response (DDR) pathways, increases DNA damage, and interacts with Chk2 and Chk1 to facilitate viral replication and cell cycle arrest.

bioRxiv · Apr 12, 2022Microbiology

MK2a inhibitor CMPD1 abrogates chikungunya virus infection by modulating actin remodeling pathway

S. Chattopadhyay, P. Mamidi, T. K. Nayak, A. Kumar, S. Kumar, S. Chatterjee, S. De, A. Datey, E. Laha, A. Ray, S. Chattopadhyay

This study shows that MK2 and MK3 inhibition with CMPD1 reduces CHIKV infection by blocking actin remodeling and viral release, with potential for antiviral development.

bioRxiv · May 26, 2021Microbiology

Autoimmunity Risk Gene IRGM is a Master Negative Regulator of Interferon Response by Controlling the Activation of cGAS STING and RIG-I-MAVS Signaling Pathways

K. K. Jena, S. Mehto, P. Nath, N. R. Chauhan, R. Sahu, T. K. Nayak, S. K. Das, K. Dhar, P. K. Sahoo, K. C. Murmu, S. De, A. Datey, P. Prasad, S. Chattopadhyay, S. Chauhan, S. Chauhan

This study identifies IRGM as a negative regulator of interferon response by controlling cGAS-STING and RIG-I-MAVS pathways, linking its deficiency to autoimmunity and antiviral resistance.

bioRxiv · Oct 22, 2019 · PreprintImmunology