Ultra-long-acting refillable nanofluidic implant confers full protection against SHIV infection in non-human primates
F. P. Pons-Faudoa, N. Di Trani, S. Capuani, J. N. Campa-Carranza, B. Nehete, S. Sharma, K. A. Shelton, L. R. Bushman, F. Abdelmawla, M. Williams, L. Roon, D. Nerguizian, C. Y. X. Chua, M. M. Ittmann, J. E. Nichols, , A. Grattoni
An ultra-long-acting refillable nanofluidic implant sustained islatravir levels in non-human primates for 20 months and provided 100% protection against SHIV infection.
bioRxiv · Dec 15, 2022 · PreprintBioengineering