Author

M. A. Marzinke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

A. Grattoni· 1 shared A. Sizovs· 1 shared B. Grasperge· 1 shared C. M. Cain· 1 shared C. Y. X. Chua· 1 shared D. Karunakaran· 1 shared D. Watrous· 1 shared E. Bryndza-Tfaily· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. Grattoni

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Author profile →

2 papers

Recent·Most cited

Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates

F. P. Pons-Faudoa, A. Sizovs, K. A. Shelton, Z. Momin, L. R. Bushman, J. Xu, C. Y. X. Chua, J. E. Nichols, T. Hawkins, J. F. Rooney, M. A. Marzinke, J. T. Kimata, P. L. Anderson, P. N. Nehete, R. C. Arduino, , A. Grattoni

This study evaluates a long-acting tenofovir alafenamide nanofluidic implant in nonhuman primates, showing partial protection against SHIV infection.

bioRxiv · May 13, 2020Bioengineering

A Subcutaneous Implant of Tenofovir Alafenamide Fumarate Causes Local Inflammation and Tissue Necrosis in Rabbits and Macaques

J. Su, S. M. Simpson, S. Sung, E. Bryndza-Tfaily, R. S. Veazey, M. A. Marzinke, J. Qiu, D. Watrous, L. Widanapathirana, E. Pearson, M. M. Peet, D. Karunakaran, B. Grasperge, G. Dobek, C. M. Cain, , P. F. Kiser

This study evaluates a subcutaneous TAF implant for HIV prevention, finding it achieves sustained drug levels but causes severe local inflammation and necrosis in rabbits and macaques.

bioRxiv · Sep 19, 2019Pharmacology & Toxicology