P. Nagarajan

A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis

Dynamic Reassociation of the Nuclear Lamina with Newly Replicated DNA

The paper investigates DNA-nuclear lamina interactions during replication and finds that lamin A/C, lamin B, LBR, and emerin associate with newly replicated DNA, with reassociation taking about 30 minutes.

A Novel congenic Mouse Model to study Obesity, Diabetes and NAFLD

This study creates a congenic mouse model with Lepr mutation on WSB/EiJ background to study obesity, finding it develops obesity but not diabetes or NAFLD.

Selective estrogen receptor modulators limit alphavirus infection by targeting the viral capping enzyme nsP1

This study shows that SERMs inhibit alphavirus infection by targeting the viral capping enzyme nsP1, with antiviral effects observed in cell culture and mice.

Histone Acetyltransferase 1 is Required for DNA Replication Fork Function and Stability

This study shows that Hat1 is essential for DNA replication fork stability and proper histone acetylation during chromatin assembly.

Hat1-Dependent Lysine Acetylation Targets Diverse Cellular Functions

This study identifies Hat1-dependent lysine acetylation targets across diverse cellular functions using proteomics in mouse cells.