Author

P. Rothe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. Halbedel· 4 shared J. Rismondo· 2 shared S. Wamp· 2 shared A. Grundling· 1 shared A. Gründling· 1 shared A. Thuermer· 1 shared G. Holland· 1 shared J. Doellinger· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

S. Halbedel

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Author profile →

4 papers

Recent·Most cited

Cytosolic factors controlling PASTA kinase-dependent ReoM phosphorylation

P. Rothe, S. Wamp, L. Rosemeyer, J. Rismondo, J. Doellinger, A. Grundling, S. Halbedel

This study identifies GpsB as an activator of PrkA, a PASTA kinase, and shows that ReoM phosphorylation is regulated by growth phase and phosphatase PrpC, with MurA's conformation and interaction with ReoM playing a key role.

bioRxiv · Apr 2, 2024Microbiology

Imbalance of peptidoglycan biosynthesis alters the cell surface charge of Listeria monocytogenes

L. M. Schulz, P. Rothe, S. Halbedel, A. Gründling, J. Rismondo

This study shows that EslB deficiency in Listeria monocytogenes leads to thinner peptidoglycan and increased negative surface charge, enhancing lysozyme sensitivity.

bioRxiv · Sep 13, 2022Microbiology

Listeria monocytogenes gene essentiality under laboratory conditions and during macrophage infection

M. A. Fischer, T. Engelgeh, P. Rothe, S. Fuchs, A. Thuermer, S. Halbedel

This study identifies essential genes for Listeria monocytogenes growth in laboratory conditions and during macrophage infection using Tn-Seq.

bioRxiv · Mar 4, 2022Microbiology

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

S. Wamp, P. Rothe, G. Holland, S. Halbedel

The paper identifies murA escape mutations in L. monocytogenes that prevent proteolytic degradation of MurA, constitutively activating peptidoglycan biosynthesis and enhancing cephalosporin resistance.

bioRxiv · Sep 9, 2021Microbiology