Author

A. Gründling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Rismondo· 2 shared L. M. Schulz· 2 shared A. Nolan· 1 shared A. Wadhawan· 1 shared C. Campbell· 1 shared I. Kviatkovski· 1 shared J. P. O'Gara· 1 shared L. Urwin· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

J. Rismondo

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Author profile →

3 papers

Recent·Most cited

Imbalance of peptidoglycan biosynthesis alters the cell surface charge of Listeria monocytogenes

L. M. Schulz, P. Rothe, S. Halbedel, A. Gründling, J. Rismondo

This study shows that EslB deficiency in Listeria monocytogenes leads to thinner peptidoglycan and increased negative surface charge, enhancing lysozyme sensitivity.

bioRxiv · Sep 13, 2022Microbiology

Purine nucleosides interfere with c-di-AMP levels and act as adjuvants to re-sensitize MRSA to β-lactam antibiotics

A. Nolan, M. S. Zeden, C. Campbell, I. Kviatkovski, L. Urwin, R. M. Corrigan, A. Gründling, J. P. O'Gara

This study shows that purine nucleosides like guanosine and xanthosine reduce β-lactam resistance in MRSA by lowering c-di-AMP levels, acting as adjuvants to restore antibiotic effectiveness.

bioRxiv · Sep 1, 2022 · PreprintMicrobiology

EslB is required for cell wall biosynthesis and modification in Listeria monocytogenes

J. Rismondo, L. M. Schulz, M. Yacoub, A. Wadhawan, M. Hoppert, M. S. Dionne, A. Gründling

This study shows that EslB, a component of the ABC transporter EslABC, is essential for cell wall biosynthesis and modification in L. monocytogenes, affecting lysozyme resistance, cell division, and growth in high-sugar media.

bioRxiv · Feb 3, 2020Microbiology