Author

M. A. Fischer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. Halbedel· 2 shared A. Flieger· 1 shared A. Fruth· 1 shared A. G. Kansy· 1 shared A. Piee-Staffa· 1 shared A. Thuermer· 1 shared A.-H. M. Mustafa· 1 shared B. N. Smith· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

S. Halbedel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Type I interferon induces TCR-dependent and -independent antimicrobial responses in γδ intraepithelial lymphocytes

M. A. Fischer, L. Jia, K. L. Edelblum

This study shows type I interferon induces antimicrobial responses in γδ IELs both independently and dependently on TCR signaling.

bioRxiv · Mar 11, 2024 · PreprintImmunology

Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells

M. A. Fischer, A.-H. M. Mustafa, K. Hausmann, R. Ashry, A. G. Kansy, M. C. Liebl, C. Brachetti, A. Piee-Staffa, M. Zessin, H. S. Ibrahim, T. G. Hofmann, M. Schutkowski, W. Sippl, O. H. Kramer

This paper synthesizes novel HDAC inhibitors that show nanomolar activity against class I HDACs and induce apoptosis while constraining autophagy in leukemic cells.

bioRxiv · Mar 9, 2023Pharmacology & Toxicology

Listeria monocytogenes gene essentiality under laboratory conditions and during macrophage infection

M. A. Fischer, T. Engelgeh, P. Rothe, S. Fuchs, A. Thuermer, S. Halbedel

This study identifies essential genes for Listeria monocytogenes growth in laboratory conditions and during macrophage infection using Tn-Seq.

bioRxiv · Mar 4, 2022Microbiology

MCL1 dependence across MDS subtypes and dual inhibition of MCL1 and BCL2 in MISTRG6 mice

M. A. Fischer, Y. Song, R. Gbyli, M. P. Arrate, M. T. Villaume, M. A. Childress, B. N. Smith, T. P. Stricker, S. Halene, M. R. Savona

The paper assesses MCL1 dependence in MDS subtypes and shows that combined inhibition of BCL2 and MCL1 is synergistic in vitro and reduces MDS engraftment in mice.

bioRxiv · Jun 5, 2020 · PreprintCancer Biology

Population structure-guided profiling of antibiotic resistance patterns in clinical Listeria monocytogenes isolates from Germany identifies pbpB3 alleles associated with low levels of cephalosporin resistance

M. A. Fischer, S. Wamp, A. Fruth, F. Allerberger, A. Flieger, S. Halbedel

The paper analyzes antibiotic resistance in Listeria monocytogenes isolates from Germany, identifying pbpB3 alleles linked to reduced cephalosporin resistance.

bioRxiv · May 25, 2020Microbiology