The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity
D. Pezic, S. Weeks, W. Varsally, P. S. Dewari, M. Branco, S. HADJUR
This study identifies the N-terminus of Stag1 as critical for maintaining nucleolar integrity and repressing the 2C program in mESCs by regulating rRNA expression and preventing totipotency.
bioRxiv · Feb 14, 2021Cell Biology