Author

S. HADJUR

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. Pezic· 2 shared W. Varsally· 2 shared A. Bhamra· 1 shared A. Gutierrez· 1 shared A. K. Fielding· 1 shared A. Turna· 1 shared D. O'Connor· 1 shared G. Bloye· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

D. Pezic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia

S. Rahman, G. Bloye, N. Farah, J. Demeulemeester, J. R. Costa, D. O'Connor, R. Pocock, A. Turna, L. Wang, S. Lee, A. K. Fielding, J. Roels, R. Jaksik, M. Dawidowska, P. V. Vlierberghe, , M. R. Mansour

The paper identifies a novel mechanism where focal deletions of an intronic element in FTO lead to IRX3 activation in T-ALL through enhancer hijacking.

bioRxiv · Feb 6, 2024Cancer Biology

Cohesin-independent STAG proteins interact with RNA and localise to R-loops to promote complex loading.

H. Porter, Y. Li, W. Varsally, M. V. Neguembor, M. Beltran, D. Pezic, L. Martin, M. Tavares Cornejo, A. Bhamra, S. Surinova, R. G. Jenner, M. P. Cosma, S. HADJUR

The paper shows SA proteins interact with RNA and R-loops to promote cohesin loading independently of NIPBL, revealing a new role in chromatin structure and cancer biology.

bioRxiv · Feb 20, 2021Cell Biology

The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity

D. Pezic, S. Weeks, W. Varsally, P. S. Dewari, M. Branco, S. HADJUR

This study identifies the N-terminus of Stag1 as critical for maintaining nucleolar integrity and repressing the 2C program in mESCs by regulating rRNA expression and preventing totipotency.

bioRxiv · Feb 14, 2021Cell Biology