Author

P. Saintigny

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Puisieux· 2 shared C. Caux· 2 shared M.-C. Michallet· 2 shared A. Coutant· 1 shared A. Karabajakian· 1 shared A. Mock· 1 shared A. Sanlaville· 1 shared A. Shnerb· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

A. Puisieux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatial transcriptomics reveal pitfalls and opportunities for the detection of rare high-plasticity breast cancer subtypes

A. Coutant, V. Cockenpot, L. Muller, C. Degletagne, R. Pommier, L. Tonon, M. Ardin, M.-C. Michallet, C. Caux, M. Laurent, A.-P. Morel, P. Saintigny, A. Puisieux, M. Ouzounova, P. Martinez

The paper uses spatial transcriptomics to identify specific markers for rare high-plasticity breast cancer subtypes, showing that bulk expression signatures are limited by stromal contamination.

bioRxiv · Apr 24, 2023Cancer Biology

CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

A. Sanlaville, A. Voissiere, D. Poujol, M. Hubert, S. Andre, C. Perret, J.-P. Foy, N. Goutagny, M. Malfroy, I. Durand, M. Chalons, J. Valladeau-Guilemond, P. Saintigny, A. Puisieux, C. Caux, , N. Bendriss-Vermare

The paper shows CD4 T cells and neutrophils promote EMT in breast cancer by analyzing murine tumor models and human cohorts.

bioRxiv · Feb 15, 2023 · PreprintCancer Biology

MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer

M. Prasad, J. Zorea, S. Jagadeeshan, A. Shnerb, J. Bouaoud, L. Michon, O. Novoplansky, M. Badarni, L. Cohen, K. Yagodayev, S. Tzadok, B. Rotblat, L. Brezina, A. Mock, A. Karabajakian, , M. Elkabets

This study shows that MEK1/2 inhibition temporarily improves the tumor immune microenvironment, enhancing immunotherapy effectiveness in head and neck cancer by reducing suppressive myeloid cells and boosting CD8+ T cell activity.

bioRxiv · Aug 22, 2021Cancer Biology