Author

I. Goswami

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:organoid / primary culture· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. Healy· 2 shared A. Laemmle· 1 shared A. Safina· 1 shared B. Siemons· 1 shared C. S. Lee· 1 shared E. C. Gomez· 1 shared E. de Klerk· 1 shared E. Miller· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

K. Healy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multiplexed microfluidic platform for stem-cell derived pancreatic islet β cells

I. Goswami, E. de Klerk, P. Carnese, M. Hebrok, K. Healy

This paper introduces a scalable microfluidic platform for culturing stem-cell derived β cells, demonstrating viability and functionality over a week and showing responses to drug exposure and metabolic challenges.

bioRxiv · May 23, 2022Bioengineering

A thermodynamic scaling law for electrically perturbed lipid membranes: validation with the steepest-entropy-ascent framework

I. Goswami, R. Bielitz, S. S. Verbridge, M. R. von Spakovsky

The paper introduces a scaling law based on the Ising model to predict the effects of pulsed electric fields on lipid membranes, validated using the steepest-entropy-ascent framework.

bioRxiv · Dec 3, 2020Biophysics

Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction

F. T. Lee-Montiel, A. Laemmle, L. Dumont, C. S. Lee, N. Huebsch, V. Charwat, H. Okochi, M. J. Hancock, B. Siemons, S. C. Boggess, I. Goswami, E. Miller, H. Willenbring, K. Healy

The paper integrates hiPSC-based liver and heart microphysiological systems to predict drug-drug interactions, showing ketoconazole inhibits cisapride metabolism, causing arrhythmia in cardiac MPSs.

bioRxiv · May 24, 2020 · PreprintBioengineering

Prevention of chromatin destabilization by FACT is crucial for malignant transformation

P. Sandlesh, A. Safina, I. Goswami, L. Prendergast, S. Rosario, E. C. Gomez, J. Wanf, K. V. Gurova

The paper shows that FACT prevents chromatin destabilization in transformed cells, which is crucial for malignant transformation and survival.

bioRxiv · Dec 17, 2018Cell Biology