Author

P. Sims

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Dovas· 2 shared P. Canoll· 2 shared A. Haddock· 1 shared A. Kannan· 1 shared A. Lassman· 1 shared A. Mahajan· 1 shared a. r. goldberg· 1 shared A. Save· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

A. Dovas

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Author profile →

2 papers

Recent·Most cited

Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence

S. S. Rosenfeld, N. Zarco, A. Dovas, V. Farias, N. Nagaiah, A. Haddock, P. Sims, D. Hambardzumyan, C. T. Meyer, P. Canoll, R. Kenchappa

This study identifies STAT3 as a key driver of resistance to spindle inhibitors in glioblastoma, showing that therapy-induced senescence contributes to drug resistance by promoting quiescence and secreting factors that induce quiescence in proliferating cells.

bioRxiv · Jun 9, 2024Cancer Biology

Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic andtargetable tissue states

O. Al-Dalahmah, M. Argenziano, A. Kannan, A. Mahajan, J. Furnari, F. Paryani, D. Boyett, A. Save, N. Humala, F. Khan, J. Li, H. Lu, Y. Sun, J. Tuddenham, a. r. goldberg, , P. Canoll

The paper identifies three tissue states in glioblastoma microenvironments using snRNAseq and spatial transcriptomics, linking them to metabolic pathways and clinical outcomes.

bioRxiv · Jul 6, 2021Pathology