S. S. Rosenfeld

Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma

This study uses lineage tracing and scRNA-seq to analyze drug resistance in glioblastoma cells treated with KIF11 inhibitor ispinesib, finding resistance-associated phenotypic changes and potential drug combinations.

Differential migration mechanics and immune responses of glioblastoma subtypes

This study shows mesenchymal glioblastoma cells migrate faster and generate more traction force than proneural cells, but their immunologically hot environment improves survival despite aggressive growth.

The mechanochemical origins of the microtubule sliding motility within the kinesin-5 domain organization

This study investigates how the structural features of kinesin-5, specifically tail-motor domain interactions and minifilament length, influence microtubule sliding motility and spindle organization.

The mechanism of selective kinesin inhibition by kinesin binding protein.

This study identifies how kinesin binding protein selectively inhibits specific kinesins by structurally distorting their motor domains and blocking microtubule attachment.