Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
14 papers
Recent·Most cited
S. E. Champer, B. Chae, B. C. Haller, J. Champer, P. W. Messer
This paper introduces a resource-explicit modeling method for spatial population models that improves computational efficiency while maintaining accuracy.
Methods in Ecology and Evolution · Dec 1, 2024Peer-reviewedEcology
A. J. Lea, I. V. Caldas, K. M. Garske, J. Echwa, M. Gurven, C. Handley, J. Kahumbu, J. Kamau, P. Kinyua, F. Lotukoi, A. Lopurudoi, S. Lowasa, R. Mallarino, D. Martins, P. W. Messer, , J. F. Ayroles
The paper identifies genetic regions associated with adaptation to water stress and pastoralism in the Turkana people using genome sequencing.
bioRxiv · Jan 17, 2023Evolutionary Biology
I. V. Caldas, A. G. Clark, P. W. Messer
This paper develops a machine learning method to infer selective sweep parameters from genetic data, accurately classifying sweep types and estimating selection coefficients.
bioRxiv · Jul 19, 2022 · PreprintEvolutionary Biology
A. M. Langmüller, J. Champer, S. Lapinska, L. Xie, M. Metzloff, J. Liu, Y. Xu, A. G. Clark, P. W. Messer
This study evaluates fitness costs of CRISPR/Cas9 in Drosophila by tracking allele frequencies of transgenic constructs, finding moderate off-target costs but no direct Cas9 costs, with Cas9HF1 minimizing off-target effects.
bioRxiv · May 13, 2021Evolutionary Biology
S. E. Champer, N. Oakes, R. Sharma, P. Garcia-Diaz, J. Champer, P. W. Messer
The paper models CRISPR gene drives for rodent population suppression and finds they can eliminate island populations if resistance is minimized.
bioRxiv · Nov 5, 2020 · PreprintEcology
N. R. Garud, P. W. Messer, D. A. Petrov
The paper reanalyzes Drosophila melanogaster population genomic data to confirm that recent and strong sweeps are likely soft sweeps, despite criticism of the original findings.
bioRxiv · Jun 20, 2020Evolutionary Biology
J. R. Adrion, C. B. Cole, N. Dukler, J. G. Galloway, A. L. Gladstein, G. Gower, C. C. Kyriazis, A. P. Ragsdale, G. Tsambos, F. Baumdicker, J. Carlson, R. A. Cartwright, A. Durvasula, I. Gronau, B. Y. Kim, , A. D. Kern
The paper introduces stdpopsim, a community-maintained library for population genetic models, to standardize simulations and facilitate benchmarking of inference tools.
bioRxiv · Dec 20, 2019Evolutionary Biology
J. Champer, I. Kim, S. Champer, A. G. Clark, P. W. Messer
This study shows that suppression gene drives in spatial models can lead to unstable persistence of both drive and wild-type alleles due to chasing dynamics.
bioRxiv · Sep 14, 2019Ecology
R. N. Lou, N. O. Therkildsen, P. W. Messer
This study shows how trait genetic architecture affects QTL detection power in artificial selection experiments and provides a simulation framework for optimizing experimental design.
bioRxiv · Jun 15, 2019Evolutionary Biology
B. C. Haller, J. Galloway, J. Kelleher, P. W. Messer, P. L. Ralph
The paper implements tree-sequence recording in SLiM 3 to improve computational efficiency and enable new analyses of whole-genome simulations.
bioRxiv · Nov 6, 2018Evolutionary Biology
J. Liu, J. Champer, C. Liu, J. Chung, R. Reeves, A. Luthra, Y. L. Lee, A. G. Clark, P. W. Messer
The paper develops a maximum likelihood framework to estimate fitness components in experimental evolution using Drosophila melanogaster data, finding reduced mating preference and viability for a yellow allele.
bioRxiv · Jun 14, 2018Evolutionary Biology
D. Duneau, S. Haina, J. Revah, K. San Miguel, H. D. Kunerth, I. V. Calvas, P. W. Messer, J. Scott, N. Buchon
This study identifies genetic mutations associated with resistance to two insecticides in Drosophila melanogaster using GWAS and finds that resistance mechanisms differ between insecticide classes.
bioRxiv · Mar 23, 2018Evolutionary Biology