Author

Y. L. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Pathak· 2 shared J. Mathur· 2 shared A. G. Clark· 1 shared A. Luthra· 1 shared B. Sarker· 1 shared C. Liu· 1 shared C. Walter· 1 shared H. Zmuda· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

A. Pathak

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanically primed cells transfer memory to fibrous matrices for persistent invasion

J. Almeida, J. Mathur, Y. L. Lee, B. Sarker, A. Pathak

The paper shows that cells primed by stiff matrices apply higher forces and align collagen fibers for sustained invasion, demonstrating mechanical memory transfer between cells and matrices.

bioRxiv · May 2, 2022 · PreprintBiophysics

Matrix obstructions cause multiscale disruption in collective epithelial migration by suppressing physical function of leader cells

Y. L. Lee, J. Mathur, C. Walter, H. Zmuda, A. Pathak

This study shows that dense matrix obstructions disrupt collective epithelial migration by altering cell stiffness, leader-follower dynamics, and communication, with implications for disease mechanotypes.

bioRxiv · Apr 28, 2022Biophysics

Maximum likelihood estimation of fitness components in experimental evolution

J. Liu, J. Champer, C. Liu, J. Chung, R. Reeves, A. Luthra, Y. L. Lee, A. G. Clark, P. W. Messer

The paper develops a maximum likelihood framework to estimate fitness components in experimental evolution using Drosophila melanogaster data, finding reduced mating preference and viability for a yellow allele.

bioRxiv · Jun 14, 2018Evolutionary Biology