Crystal Structure of the Werner's Syndrome Helicase
J. A. Newman, A. E. Gavard, S. Lieb, M. C. Ravichandran, K. Hauer, P. Werni, L. Geist, J. Boettcher, J. R. Engen, K. Rumpel, M. Samwer, M. Petronczki, O. Gileadi
This study determines the crystal structure of the WRN helicase core and identifies structural features that may aid in designing inhibitors against WRN helicase.
bioRxiv · May 4, 2020 · PreprintBiochemistry