Author

A. E. Gavard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 2

Frequent Co-Authors

J. A. Newman· 2 shared O. GileadiiD· 2 shared A. A. Dannerfjord· 1 shared C. J. Schofield· 1 shared H. T. Baddock· 1 shared J. Boettcher· 1 shared J. R. Engen· 1 shared K. Hauer· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

J. A. Newman

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2 papers

Recent·Most cited

Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition

Y. Yosaatmadja, H. T. Baddock, J. A. Newman, M. Bielinski, A. E. Gavard, S. M. M. Mukhopadhyay, A. A. Dannerfjord, C. J. Schofield, P. J. McHugh, O. Gileadi

This study presents crystal structures of Artemis variants and identifies a unique metal binding site, providing insights for inhibitor development.

bioRxiv · Jan 8, 2021Biochemistry

Crystal Structure of the Werner's Syndrome Helicase

J. A. Newman, A. E. Gavard, S. Lieb, M. C. Ravichandran, K. Hauer, P. Werni, L. Geist, J. Boettcher, J. R. Engen, K. Rumpel, M. Samwer, M. Petronczki, O. Gileadi

This study determines the crystal structure of the WRN helicase core and identifies structural features that may aid in designing inhibitors against WRN helicase.

bioRxiv · May 4, 2020 · PreprintBiochemistry