S. Zientara

A Machine Learning Framework to Identify the Correlates of Disease Severity in Acute Arbovirus Infection

This study uses machine learning to identify key viral and host processes associated with varying severity in bluetongue virus infection in sheep.

First Detection of Epizootic Haemorrhagic Disease virus in the European Union, Italy-2022.

The paper reports the first detection of EHDV-8 in the EU, identifying its origin as Northern Africa with high genetic similarity to Tunisian strains.

Replication of Equine arteritis virus is efficiently suppressed by purine and pyrimidine biosynthesis inhibitors

This study identifies three compounds that suppress EAV replication in equine cells, including ribavirin and DHODH inhibitors, offering potential antiviral strategies for EAV outbreaks.

Evolutionary stasis of an RNA virus indicates arbovirus re-emergence triggered by accidental release

This study uses genomic data to show that a BTV-8 virus strain re-emerged in 2015 without significant evolution, suggesting accidental release rather than natural persistence.

Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway

This paper identifies BTV-NS3 as a virulence factor that activates the MAPK/ERK pathway via interaction with BRAF, promoting viral replication and inflammation.