Comprehensive assessment of Indian variations in the druggable kinome landscape highlights distinct insights at the sequence, structure and pharmacogenomic stratum
Gayatri Panda, Neha Mishra, Disha Sharma, Rintu Kutum, Rahul C. Bhoyar, Abhinav K. Jain, Mohamed Imran, Vigneshwar Senthilvel, Mohit Kumar Divakar, Anushree Mishra, Parth Garg, Priyanka Banerjee, Sridhar Sivasubbu, Vinod Scaria, Arjun Ray
This study analyzes Indian genetic variations in the kinome to identify sequence, structural, and pharmacogenomic differences compared to global datasets, highlighting implications for drug safety and adverse reactions.
Frontiers in Pharmacology · Jul 5, 2022Peer-reviewedGenomics