MicrobiologymBioPeer-reviewed
Blocking HXA3-mediated neutrophil elastase release during S. pneumoniae lung infection limits pulmonary epithelial barrier disruption and bacteremia
Shuying Xu, Shumin Tan, Patricia Romanos…·John M. Leong
This study identifies HXA3 as a driver of neutrophil transmigration and elastase release during pneumococcal infection, showing that blocking these processes reduces epithelial damage and bacteremia.
8 citations