Author

Michael K. Mansour

Harvard UniversityORCID 0000-0001-8892-8695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexander Morris· 1 shared Allison K. SchereriD· 1 shared Anne Gumina· 1 shared Anthony Ducasse· 1 shared Brian C. RussoiD· 1 shared D. SykesiD· 1 shared David M. MarkovitziD· 1 shared David T. ScaddeniD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Alexander Morris

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedAug 9, 2024

Blocking HXA3-mediated neutrophil elastase release during S. pneumoniae lung infection limits pulmonary epithelial barrier disruption and bacteremia

Shuying Xu, Shumin Tan, Patricia Romanos…·John M. Leong

This study identifies HXA3 as a driver of neutrophil transmigration and elastase release during pneumococcal infection, showing that blocking these processes reduces epithelial damage and bacteremia.

8 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyFrontiers in ImmunologyPeer-reviewedJul 30, 2024

Vimentin regulates mitochondrial ROS production and inflammatory responses of neutrophils

Thao Ngoc Huynh, Jody D. Toperzer, Allison K. Scherer…·Brian C. Russo

This study shows vimentin regulates neutrophil mitochondrial ROS production and inflammatory responses by modulating mitochondrial function and ROS levels.

13 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivFeb 29, 2024

Multiomic analysis of clonal development reveals new regulators of leukemic cell growth

Gracia M. Bonilla, Alexander Morris, Sharmistha Kundu…·Ruslan I. Sadreyev

The paper uses multiomic analysis of leukemic clones in a mouse model to identify growth regulators and validate their roles in AML.

1 citation

mouseChIP-seq

𝕏 PostBluesky