Activity-dependent netrin-1 secretion drives synaptic insertion of GluA1-containing AMPA receptors in the hippocampus.
Stephen D. Glasgow, Simon Labrecque, Ian V. Beamish, Sarah Aufmkolk, Julien Gibon, Dong Cho Han, Stephanie N. Harris, Paul Dufresne, Paul W. Wiseman, Rebecca Anne McKinney, Philippe Séguéla, Paul De Koninck, Edward S. Ruthazer, Timothy E. Kennedy
This study identifies netrin-1 as an activity-dependent effector of synaptic plasticity by promoting GluA1-containing AMPAR insertion at hippocampal synapses.
Cell Reports · Oct 1, 2018Peer-reviewedNeuroscience