Edward S. Ruthazer

This study shows norepinephrine activates radial astrocytes in the optic tectum, altering visual processing to enhance threat detection and escape behavior in developing Xenopus laevis.

The paper examines parallel morphological and functional development in the Xenopus retinotectal system by combining calcium imaging with structural imaging.

This study shows acetylcholine and netrin-1 work together to enable persistent firing in the entorhinal cortex, essential for spatial working memory.

This study investigates BDNF signaling's role in structural plasticity during visual system development by manipulating neural activity correlation and observing axonal branch dynamics in Xenopus laevis tadpoles.

This study investigates how patterned visual experience affects early myelin ensheathment in Xenopus tadpoles by manipulating neuronal activity with strobe light and measuring calcium responses.

The paper shows that sodium-calcium exchangers (NCX) are critical for visually-evoked calcium transients in radial astrocytes during Xenopus laevis retinotectal development.

This study examines how chronic D-serine administration affects the structure and function of the developing optic tectum in Xenopus, showing changes in dendritic morphology and retinotopic map organization.

The paper observes microglial trogocytosis of axons in vivo and identifies complement regulatory proteins that modulate this process and axonal pruning.

The paper introduces two improved near-infrared calcium indicators for better neuronal activity imaging in vivo.

This study identifies distinct pre- and post-synaptic roles of DCC in hippocampal synaptic plasticity and spatial memory in adult mice.

This study shows that netrin-1 expressed by neurons in the adult brain is critical for spatial memory formation, as its deletion impairs memory without affecting anxiety or grooming behavior.

This study identifies netrin-1 as an activity-dependent effector of synaptic plasticity by promoting GluA1-containing AMPAR insertion at hippocampal synapses.