Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning
Nadine Körtel, Cornelia Rücklé, You Zhou, Anke Busch, Peter Hoch-Kraft, F.X. Reymond Sutandy, Jacob Haase, Mihika Pradhan, Michael U. Musheev, Dirk H. Ostareck, Antje Ostareck‐Lederer, Christoph Dieterich, Stefan Hüttelmaier, Christof Niehrs, Oliver Rausch, , Kathi Zarnack
The paper improves m6A RNA modification detection using miCLIP2 and m6Aboost, identifying thousands of high-confidence sites in human and mouse cells without requiring Mettl3 depletion.
Nucleic Acids Research · Jun 7, 2021Peer-reviewedGenomics