Oliver Rausch

This study shows that inhibiting METTL3 with STC-15 causes RNA misprocessing, leading to dsRNA formation and activation of innate immunity in cancer cells.

This study shows that the RBM15-MKL1 fusion protein drives leukemia through m6A methylation and WNT pathway activation, with METTL3 inhibition reducing tumor growth.

This study uses machine learning to predict genes associated with RNA methylation pathways in humans using multi-omics data from the Harmonizome database.

The paper improves m6A RNA modification detection using miCLIP2 and m6Aboost, identifying thousands of high-confidence sites in human and mouse cells without requiring Mettl3 depletion.