Cornelia Rücklé

Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning

The paper improves m6A RNA modification detection using miCLIP2 and m6Aboost, identifying thousands of high-confidence sites in human and mouse cells without requiring Mettl3 depletion.

Makorin1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation

This study shows that Makorin1 promotes oskar translation by displacing Bruno from its 3' UTR, essential for embryonic patterning and germ cell formation in Drosophila.

The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A)-translation

This study identifies MKRN1 as a key player in ribosome-associated quality control by promoting ribosome stalling at poly(A) sequences to prevent erroneous protein production.