The earliest changes in the translatome upon human T cell activation
Alexey V. Stepanov, Aoife O’Connell, Phil O’Brien, Patrick B. F. O’Connor, Alla D. Fedorova, Audrey M. Michel, Pavel V. Baranov, Yury P. Rubtsov, Gary Loughran, Dmitry E. Andreev
This study examines early transcriptional and translational changes in human T cells within four hours of activation, revealing dynamic gene expression and translation initiation patterns.
bioRxiv · Jul 31, 2025 · PreprintImmunology