Author

Pim W. Toonen

Royal Netherlands Academy of Arts and Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ajit I. QuirindongoiD· 1 shared Alain de BruiniD· 1 shared Aniek JansseniD· 1 shared Banafsheh Etemad· 1 shared Bastiaan van Gerwen· 1 shared Geert J.P.L. KopsiD· 1 shared Lodewijk A.A. BrosensiD· 1 shared Marco António Dias LouroiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ajit I. QuirindongoORCID

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1 paper

Recent·Most cited

Non-cell-autonomous mechanisms of tumor initiation and relapse by chromosomal instability

Simona Jole Anna Lafirenze, Bastiaan van Gerwen, Ajit I. Quirindongo, Natasja G. J. Costermans, Aniek Janssen, Banafsheh Etemad, Pim W. Toonen, Marco António Dias Louro, Wilma H. M. Hoevenaar, Sameh A. Youssef, Alain de Bruin, Lodewijk A.A. Brosens, Nannette Jelluma, Geert J.P.L. Kops

This study shows that chromosomal instability (CIN) can both promote and suppress tumor formation depending on its level, with high CIN acting non-cell-autonomously to drive tumor relapse.

Proceedings of the National Academy of Sciences · Jun 17, 2026Peer-reviewedCancer Biology