BiophysicsbioRxivPreprint
Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance
Danny Muzata, Dwipanjan Sanyal, Arti Shivram…·Sourav Chowdhury
This study uses computational methods to analyze the mutational landscape of Plasmodium falciparum DHFR, revealing evolutionary pathways and co-evolving networks that contribute to antifolate resistance.
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