Author

Aneesh Sreevallabh Chivukula

Birla Institute of Technology and Science, PilaniORCID 0000-0002-0445-4435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Approach:deep learning· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Arti Shivram· 2 shared Danny MuzataiD· 2 shared Deeptanshu PandeyiD· 2 shared Dwipanjan SanyaliD· 2 shared Ravi JasujaiD· 2 shared Sourav ChowdhuryiD· 2 shared Vladimir Nikolaevich UverskyiD· 2 shared Daniel Craig ZielinskiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiophysics

Arti Shivram

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2 papers

Recent·Most cited

BiophysicsInternational Journal of Biological MacromoleculesPeer-reviewedApr 18, 2025

Mapping DHPS Evolvability: Identification of Novel Evolutionarily Critical Sub-Structure through Evolutionary and Structural Analyses of DHPS

Dwipanjan Sanyal, Arti Shivram, Deeptanshu Pandey…·Sourav Chowdhury

The paper identifies a critical substructure in DHPS through evolutionary and structural analyses, suggesting it as a target to constrain evolvability and disrupt antibiotic resistance.

4 citations

protein structureprotein sequence

𝕏 PostBluesky

BiophysicsbioRxivPreprintOct 31, 2024

Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance

Danny Muzata, Dwipanjan Sanyal, Arti Shivram…·Sourav Chowdhury

This study uses computational methods to analyze the mutational landscape of Plasmodium falciparum DHFR, revealing evolutionary pathways and co-evolving networks that contribute to antifolate resistance.

2 citations

plant (other)statistical model

𝕏 PostBluesky