RICTOR regulates an interspecies crosstalk that influences longevity through a novel methionine cycle-mitophagy axis
Simran Motwani, Somya Bhandari, Shivani Chitkara, Rajat Ujjainiya, Prerona Ghosh, Shantanu Sengupta, Arnab Mukhopadhyay
This study identifies RICTOR as a regulator of dietary plasticity in C. elegans, showing it modulates longevity through a methionine cycle-mitophagy axis influenced by bacterial vitamin B12.
Nature Communications · Sep 14, 2026Peer-reviewedCell Biology