Author

Shivani Chitkara

Academy of Scientific and Innovative ResearchORCID 0009-0003-6377-7052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Arnab MukhopadhyayiD· 2 shared Rajat UjjainiyaiD· 2 shared Shantanu SenguptaiD· 2 shared Govind PrakashiD· 1 shared Prerona Ghosh· 1 shared Rachamadugu Sai Keerthana· 1 shared Sabnam Sahin RahmaniD· 1 shared Shreya BhattacharjeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Arnab MukhopadhyayORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedSep 14, 2026

RICTOR regulates an interspecies crosstalk that influences longevity through a novel methionine cycle-mitophagy axis

Simran Motwani, Somya Bhandari, Shivani Chitkara…·Arnab Mukhopadhyay

This study identifies RICTOR as a regulator of dietary plasticity in C. elegans, showing it modulates longevity through a methionine cycle-mitophagy axis influenced by bacterial vitamin B12.

DOI 10.1038/s41467-026-77722-7

C. elegansgenetic perturbation / CRISPR

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Cell BiologyNature CommunicationsPeer-reviewedJun 2, 2025

Methionine cycle in a pair of serotonergic neurons regulates diet-dependent behavior and longevity through a neuron-gut signaling

Sabnam Sahin Rahman, Shreya Bhattacharjee, Simran Motwani…·Arnab Mukhopadhyay

This study shows that the methionine cycle in serotonergic neurons regulates diet-dependent behavior and longevity through a neuron-gut signaling pathway in C. elegans.

8 citations

C. elegansexperimental assay

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