Cancer BiologybioRxivPreprint
DR5 CAR-T cells target solid tumors and suppress MDSCs with minimal toxicity
Huaishan Wang, Shujing Liu, Prithvi Sinha…·Xiaowei Xu
This study develops DR5-targeted CAR-T cells that kill solid tumors and MDSCs, enhance CD8+ T cell activity, and show minimal toxicity in preclinical models.