Author

Xiaowei Xu

University of PennsylvaniaORCID 0000-0003-4098-7690Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiaowei Xu4 papers · Zhejiang University of Technology

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander Chan Chi HuangiD· 2 shared Giorgos Constantine KarakousisiD· 2 shared Anushka DheeriD· 1 shared Beatriz Goncalves· 1 shared Carl H. JuneiD· 1 shared Fang LiuiD· 1 shared Fei MiaoiD· 1 shared Haiwei MouiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Alexander Chan Chi HuangORCID

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2 papers

Recent·Most cited

Cellular interactions in the sentinel lymph node predict melanoma recurrence

Sabrina M. Solis, Yang Yang, Yee Hoon Foong, Anushka Dheer, Kevin L. Ma, Mohammad Saad Farooq, Shira Rosenberg, Sophie L. Gray-Gaillard, Giorgos Constantine Karakousis, Xiaowei Xu, Rami Sesha Vanguri, Alexander Chan Chi Huang, Ramin S. Herati

The paper identifies Treg-CD8 T cell interactions in the sentinel lymph node as predictors of melanoma recurrence in Stage II patients.

bioRxiv · Dec 17, 2025 · PreprintImmunology

DR5 CAR-T cells target solid tumors and suppress MDSCs with minimal toxicity

Huaishan Wang, Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo, Beatriz Goncalves, Qiuxiang Zheng, Haiwei Mou, Jingbo Yang, Lili Huang, John Scholler, Fei Miao, Tingting Zeng, Giorgos Constantine Karakousis, , Xiaowei Xu

This study develops DR5-targeted CAR-T cells that kill solid tumors and MDSCs, enhance CD8+ T cell activity, and show minimal toxicity in preclinical models.

bioRxiv · Jun 9, 2025 · PreprintCancer Biology