Author

R. A. Bragg

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Microbiology· 1

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. Delles· 1 shared C. J. Schofield· 1 shared D. M. Wall· 1 shared G. Hamm· 1 shared G. Rodriguez-Blanco· 1 shared H. Hulme· 1 shared I. P. Salt· 1 shared M. J. Ormsby· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

C. Delles

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1 paper

Recent·Most cited

Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes

M. J. Ormsby, H. Hulme, V. H. Villar, G. Hamm, G. Rodriguez-Blanco, R. A. Bragg, N. Strittmatter, C. J. Schofield, C. Delles, I. P. Salt, S. Tardito, R. Burchmore, R. J. A. Goodwin, D. M. Wall

The paper identifies two microbiome-derived metabolites, 3M-4-TMAB and 4-TMAP, that induce mitochondrial dysfunction and reduced insulin sensitivity in human liver cells, linking gut microbiota to type 2 diabetes.

bioRxiv · Aug 2, 2020 · PreprintMicrobiology