Author

V. H. Villar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. Rodriguez-Blanco· 2 shared S. Tardito· 2 shared B. A. Sterken· 1 shared C. Delles· 1 shared C. J. Schofield· 1 shared C. Nixon· 1 shared D. M. Wall· 1 shared D. Sumpton· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

G. Rodriguez-Blanco

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Author profile →

2 papers

Recent·Most cited

Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis

T. Ackermann, E. Shokry, R. Deshmukh, J. Anand, L. C. A. Galbraith, L. Mitchell, G. Rodriguez-Blanco, V. H. Villar, B. A. Sterken, C. Nixon, S. Zanivan, K. Blyth, D. Sumpton, S. Tardito

This study shows that triple-negative breast cancer cells secrete anti-ferroptotic MUFAs and rely on selenoprotein synthesis for metastasis.

bioRxiv · Jun 13, 2023Cancer Biology

Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes

M. J. Ormsby, H. Hulme, V. H. Villar, G. Hamm, G. Rodriguez-Blanco, R. A. Bragg, N. Strittmatter, C. J. Schofield, C. Delles, I. P. Salt, S. Tardito, R. Burchmore, R. J. A. Goodwin, D. M. Wall

The paper identifies two microbiome-derived metabolites, 3M-4-TMAB and 4-TMAP, that induce mitochondrial dysfunction and reduced insulin sensitivity in human liver cells, linking gut microbiota to type 2 diabetes.

bioRxiv · Aug 2, 2020 · PreprintMicrobiology