Author

I. P. Salt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. Delles· 1 shared C. J. Schofield· 1 shared D. M. Wall· 1 shared E. Higgins· 1 shared F. Alghamdi· 1 shared G. Hamm· 1 shared G. Rodriguez-Blanco· 1 shared H. Hulme· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

C. Delles

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Asymmetric dimethylarginine positively modulates Calcium-Sensing Receptor signalling to promote lipid accumulation and adiposity

L. B. Dowsett, L. Duluc, E. Higgins, F. Alghamdi, W. L. Fast, I. P. Salt, J. M. Leiper

This study shows ADMA promotes lipid accumulation and adiposity through CaSR signaling, independent of NO, by activating mTOR and lipogenic genes.

bioRxiv · Jul 26, 2022Physiology

Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes

M. J. Ormsby, H. Hulme, V. H. Villar, G. Hamm, G. Rodriguez-Blanco, R. A. Bragg, N. Strittmatter, C. J. Schofield, C. Delles, I. P. Salt, S. Tardito, R. Burchmore, R. J. A. Goodwin, D. M. Wall

The paper identifies two microbiome-derived metabolites, 3M-4-TMAB and 4-TMAP, that induce mitochondrial dysfunction and reduced insulin sensitivity in human liver cells, linking gut microbiota to type 2 diabetes.

bioRxiv · Aug 2, 2020 · PreprintMicrobiology